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Figure 5 Histograms show the signal intensity (SI) ratios after administration of the intravascular (top) and extracellular (bottom) gadolinium-chelates. T2–turbo spin echo (TSE) and the intravascular agent provided differential enhancement of acute (black bars) but not chronic (white bars) infarctions on T1-TSE and sequences. The extracellular agent provided the same magnitude of enhancement in acute and chronic infarctions on T1-TSE and inversion recovery gradient echo (IR-GRE) sequences. Note that contrast enhanced IR-GRE sequence provides better contrast than both T1-TSE and T2-TSE sequences. *p < 0.01 SI ratios compared with acute infarctions. +p < 0.01 SI ratios compared with contrast enhanced magnetic resonance imaging (MRI).
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