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Figure 4


Figure 4 Histologic sections of the stented artery from a 38-year-old woman who had undergone stenting of the proximal left anterior descending coronary artery (LAD) with a 3.0 x 12-mm Taxus stent 6 months before death. The patient had been taking clopidogrel and aspirin, but presented to a local emergency room with severe chest pain and shortly thereafter went into ventricular fibrillation and died. (A) Radiograph of the stented LAD. (B and C) Proximal and middle sections of the stented LAD stained with Movat pentachrome and hematoxylin and eosin (HE), respectively. There is total occlusion of the lumen by platelet-rich thrombus (Th) with absence of healing of the stent strut regions, which are surrounded by fibrin. The stent is placed across the orifice of the diagonal branch. High-power view of the stent struts in D (Movat) and E (HE) show peristrut fibrin with absence of smooth muscle, endothelial, and inflammatory cells.





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