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Figure 8 Representative cross-sectional (A to C) and maximum intensity projection (MIP) (D to F) images obtained from 3D micro CT scans of uninjured (A, D), stented and placebo-treated (B, E, respectively), and stented and SU11218-treated arteries (C, F, respectively). The MIP images represent a projection of image intensity along the axial direction, obtained over a 2-mm-thick sample region. Arrow = stent. I = intima; L = lumen. Adventitial microvessels (Ad-MV) (arrowhead) appear as white dots behind the stent struts in cross-sections and as bright annulus external to the stent in MIP images. There was a significant increase in Ad-MV at 4 weeks after stenting in placebo-treated animals (B, E) compared with uninjured arteries (A, D) or SU11218-treated animals (C, F). White bar = 2 mm.
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