JACC
HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK
QUICK SEARCH:   [advanced]


     

J Am Coll Cardiol, 2006; 47:470, doi:10.1016/j.jacc.2005.10.034 (Published online 20 December 2005).
© 2006 by the American College of Cardiology Foundation
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
j.jacc.2005.10.034v1
47/2/470-a    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Weissman, N. J.
Right arrow Articles by Stone, G. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Weissman, N. J.
Right arrow Articles by Stone, G. W.

CORRESPONDENCE: LETTER TO THE EDITOR

Reply

Neil J. Weissman, MD, FACC* and Gregg W. Stone, MD, FACC

* Washington Hospital Center, 110 Irving Street, NW, Suite EB-5123, Washington, DC 20010 (Email: Neil.J.Weissman{at}medstar.net).

We appreciate Dr. Kaneda’s astute observation about the data contained in our report (1) on the intravascular ultrasound (IVUS) results from TAXUS-IV. It is indeed true that there was a trend for the vessel receiving a TAXUS stent to demonstrate positive remodeling, similar to prior drug-eluting stent (DES) reports. The analysis for remodeling used only TAXUS and non-TAXUS patients with complete volumetric IVUS data of the external elastic membrane (EEM) throughout the stent length at both the time of stent implantation and at follow-up. As it states in the Methods section, "Volumes were calculated only if the vascular interface was visualized every millimeter throughout the stent" (i.e., we did not extrapolate the EEM border for images in which it was not visualized). Thus, not all patients with EEM volume data at stent implantation had EEM volume data at follow-up, and vice-versa. Table 2 of the study (1) reports all the volume data at one time point (postimplantation or follow-up) and the statistical analysis for change (and Figure 1 of the report [1] displaying change over time) used only patients that had paired postimplantation and follow-up EEM volume data. Hence, the results of a trend toward positive remodeling in the TAXUS stent are indeed accurate and in concordance with other DES studies.


   References
Top
 References
 

  1. Weissman NJ, Koglin J, Cox DA, et al. Polymer-based paclitaxel-eluting stents reduce in-stent neointimal tissue proliferationa serial volumetric intravascular ultrasound analysis from the TAXUS-IN trial. J Am Coll Cardiol 2005;45:1201-1205.[Abstract/Free Full Text]




This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
j.jacc.2005.10.034v1
47/2/470-a    most recent
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Weissman, N. J.
Right arrow Articles by Stone, G. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Weissman, N. J.
Right arrow Articles by Stone, G. W.

HOME SUBSCRIPTIONS CURRENT ISSUE PAST ISSUES CARDIOSOURCE SEARCH HELP FEEDBACK