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J Am Coll Cardiol, 2006; 47:470, doi:10.1016/j.jacc.2005.10.033 (Published online 20 December 2005).
© 2006 by the American College of Cardiology Foundation
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CORRESPONDENCE: LETTER TO THE EDITOR

Intravascular Ultrasound Analysis of Polymer-Based Paclitaxel-Eluting Stents

Hideaki Kaneda, MD*

* Cardiology and Catheterization Laboratories, ShonanKamakura General Hospital, 1202-1 Yamazaki, Kamakura, 247-8533 Japan (Email: kaneda{at}kamakuraheart.org).

With great interest I read the report by Weissman et al. (1) regarding intravascular ultrasound (IVUS) analysis of polymer-based paclitaxel-eluting stents. The investigators stated in the text that "positive remodeling assessed as the absolute increase in the external elastic membrane volume over time tended to be slightly more prominent with the TAXUS stent (7.66 ± 48.64 mm3 vs. –12.29 ± 36.05 mm3, respectively, p = 0.064)." Also Figure 1 suggested positive remodeling in the TAXUS stent. However, Table 2 of their article (1) shows an inconsistent result, that is, decrease of external elastic membrane volume in the TAXUS-stent group (283 ± 91 mm3 at postimplantation vs. 280 ± 89 mm3 at nine-month follow-up). Because a previous IVUS analysis has also suggested positive remodeling in the TAXUS stent (2), it may be of great importance to better clarify this result.


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  1. Weissman NJ, Koglin J, Cox DA, et al. Polymer-based paclitaxel-eluting stents reduce in-stent neointimal tissue proliferationa serial volumetric intravascular ultrasound analysis from the TAXUS-IV trial. J Am Coll Cardiol 2005;45:1201-1205.[Abstract/Free Full Text]
  2. Tanabe K, Serruys PW, Degertekin M, et al. Chronic arterial responses to polymer-controlled paclitaxel-eluting stents: comparison with bare metal stents by serial intravascular ultrasound analyses: data from the randomized TAXUS-II trial Circulation 2004;109:196-200.[Abstract/Free Full Text]




This Article
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