Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 1 Representative example of plaques studied. This section is representative of the plaque region analyzed. The section was stained with hematoxylin-eosin. Plaque section at low magnification. (A) A carotid plaque from a patient affected by ipsilateral major stroke who underwent carotid endarterectomy within two months of symptom onset. Fibrous cap plaque rupture with intraluminal thrombus is evident (magnification x2). (B) Carotid plaque from an asymptomatic patient, characterized by a large lipid core and a thin fibrous cap, without the presence of acute thrombus within the lumen (magnification x2). (C) Micrograph showing immunohistochemical staining of carotid plaque from patient affected by ipsilateral major stroke. Fibrous cap adjacent to rupture site containing numerous macrophage-foam cells positive to CD68 antibody (brown chromogen) (magnification x100).
|
