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Figure 3 Change in World Health Organization functional class from baseline to week 18 in the placebo, sitaxsentan 50-mg, sitaxsentan 100-mg, and open label (OL) bosentan groups. *p = 0.04 for comparison between the 100-mg dose of sitaxsentan and placebo; there was no difference for either the sitaxsentan 50-mg group or the OL bosentan group vs. placebo. BL = baseline.
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