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Figure 2 Mean (±SE) change in six-min walk (6MW) distance from baseline to week 18 in the placebo, sitaxsentan 50-mg, sitaxsentan 100-mg, and open label (OL) bosentan groups. *p = 0.03 (95% confidence interval 5.37, 57.44) for comparison between the 100-mg dose of sitaxsentan and placebo, **p = 0.05 for OL bosentan vs. placebo, and p = 0.07 for 50-mg sitaxsentan vs. placebo.
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