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Figure 2 (A) In the control group, carriers of the 807T allele (807TT + 807CT) had significantly higher levels of soluble CD40 ligand (sCD40L) compared with 807CC homozygotes in the presence of high levels of von Willebrand factor (vWF median), while there was no difference in sCD40L between genotypes among healthy individuals with vWF < median (vWF median in controls: 72.84%). (B) Carriers of the 807T allele had significantly higher levels of sCD40L compared with 807CC one year after myocardial infarction (MI) independently from plasma vWF levels (vWF median for follow-up group: 87.1%). (C) Similarly, the presence of the 807T allele was associated with higher levels of sCD40L during the acute phase of MI, independently from vWF levels (median for vWF during the acute phase of MI: 92.12%). Solid bars = Carriers of the 807T allele (807TT + 807CT); open bars = 807CC homozygotes; *p < 0.05 and **p < 0.01 vs. carriers of T allele.
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