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Figure 5 Asymmetric dimethylarginine (ADMA) inhibits endothelial nitric oxide synthase (eNOS) activity in endothelial progenitor cells (EPCs). The eNOS activity was determined in EPC cell culture supernatants by assessing the conversion of L-[guanidino-¹⁵N₂]arginine to ¹⁵N-nitrate with gas chromatography/mass spectrometry. The 15N-nitrate/14N-nitrate ratio is shown. RSV = rosuvastatin.

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