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Figure 1 Determination of collateral flow index (CFI) in a patient receiving placebo before (left) and after treatment (right). Surface (III, avF) and intracoronary (i.c.) electrocardiogram (ECG) lead recordings are shown in the upper part of the panels. After 1 min of vessel occlusion before and after treatment, there are ST-segment elevations on the i.c. ECG lead, indicating coronary collaterals insufficient to prevent myocardial ischemia. Collateral flow index is calculated by dividing distal mean coronary occlusive pressure (Poccl, mm Hg) minus central venous pressure (CVP, mm Hg) by mean aortic pressure (Pao, mm Hg) minus CVP.





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