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Figure 7 Differentiation of graft mesenchymal stem cell (MSC)HO-1 in ischemic myocardium at 14 days after transplantation. 1) Cardiac muscle differentiation. (A) DAPI-labeled nuclei is shown in blue; (B) muscle marker -actin in green; (C) cardiac marker cardiac troponin T in red; (D) Merged image of (A), (B), and (C) indicating that some graft cells adopt cardiac phenotype. Arrows point to the graft cell express cardiac mark and arrowhead indicates to host ischemic myocardium. 2: Endothelial cell differentiation. (E) DAPI-labeled nuclear; (F) endothelial marker CD31 in green; (G) Merged image of (E) and (F) indicating some graft cells participate in new microvessel formation.
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