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Figure 3 Inhibition of platelet functions in platelet-rich plasma prepared in sodium citrate (open boxes) versus r-hirudin and D-phenylalanyl-prolyl-arginine chloromethyl ketone (hirudin/PPACK) (boxes with vertical lines) (*p < 0.05). (a) Peak aggregation, (b) late aggregation, (c) P-selectin expression, (d) glycoprotein (GP) IIb/IIIa activation by monoclonal antibody binding activated GP IIb/IIIa receptors (PAC-1) measure after agonist stimulation with either a thrombin receptor activating peptide-6 (left panels) or adenosine 5'diphosphate (ADP) (right panels). Horizontal lines are medians, boxes are the interquartile range, whiskers are the 5th and 95th percentiles, and p values were obtained using the Wilcoxon signed-rank test; *p < 0.05.
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