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Figure 1 Preferential prolongation of M-cell action potential in response to a slowing of stimulation rate. Transmembrane recordings obtained from tissue slices isolated from epicardial (Epi), M, and endocardial (Endo) regions of the canine right and left ventricles at basic cycle lengths (BCLs) of 300, 1,000, 2,000, and 5,000 ms. Modified and reprinted, with permission, from Sicouri et al. (8).





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