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Figure 1 Echocardiographic measurement of akinetic area correlates with pathologic measurement of infarct size at 24 h (top panel) and 4 weeks (bottom panel) after coronary ligation. Linear regression analysis of the correlation between the percent infarction area/total ventricular area (as measured by TTC or Masson trichrome staining/histology at 24 h and 4 weeks after coronary ligation, respectively) and the percent akinetic area/total ventricular area as measured by two-dimensional echocardiography. For both timepoints n = 20 animals; 10 HIF-1 (+) (circles), 10 HIF-1(–) (triangles).
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