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Figure 1 Bar graph showing the effect of statin treatment on plasma low-density lipoprotein. Mean value of low-density lipoprotein cholesterol (LDL-C) during treatment and the pre-treatment value were used to calculate the changes. The bars describe the number of patients for a mean LDL-C at the end of treatment (A) and for the percent change in LDL-C (B). The line describes the distribution of the data. A significant decrease in LDL-C as compared with baseline was seen for both 20-mg and 80-mg simvastatin doses (A). The 80-mg simvastatin group is associated with a significantly greater 10% decline in LDL-C (B). Because of significantly higher baseline LDL-C values in the high-dose group, both groups ended in similar absolute values.
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