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Figure 2 Representative photographs of ferric chloride (FeCl3)-applied carotid arterial tissues stained with hematoxylin-eosin (A to D) and van Giesons elastin staining (F and G). In intact mice, endothelial cells were preserved in wild-type (P+/+) and P-selectin-deficient (P/) mice. However, in FeCl3-applied mice, almost no endothelial cells were observed in P+/+ and P/ mice. Note that the number of endothelial cells in P+/+ and P/ mice was significantly decreased by FeCl3 application and they were comparable (E). Furthermore, no disruptions of elastic fiber after FeCl3 application were observed in P+/+ and P/ mice (F and G).
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