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Figure 2 (A) Planscan for acquisition of transmitral flow and tissue velocities. To assess transmitral flow, a phase-contrast magnetic resonance (MR) sequence was used, with a velocity encoding of 130 cm/s and the center of the slice positioned perpendicular to mitral inflow, at early diastole (upper panel). To assess tissue MR velocities, phase-contrast MR was repeated with a velocity encoding of 30 cm/s, and the image slice positioned at two-thirds of the long axis, planned on early diastolic two- and four-chamber images, perpendicular to the interventricular septum (lower panel). (B) Velocity-encoded images of transmitral flow (upper panel) and tissue velocities (lower panel). The tissue velocities are measured from a circular region-of-interest of 20 pixels in the posteroseptal region. (C) Corresponding velocity versus time curves. From these curves, peak mitral velocity in early diastole (E) = 103 cm/s, early diastolic posteroseptal tissue velocity Ea = 8.9 cm/s and E/Ea = 11.6 were derived. Ea = early diastolic tissue velocity; Venc = velocity encoding.
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