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Figure 2 The effect of aortic insufficiency (AI). (A) Compares AI to the normal. In AI the pressure-volume "box" is wider due to the volume overload and taller due to the afterload increase. These increase end-systolic (ESV) and end-diastolic (EDV) volumes. The overall ejection fraction (EF) is generally elevated. In (B), as the slope of the line of contractility drops, the ESV has to rise, and the EF has to fall.
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