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Figure 2 Comparison of blood pressure (BP)-lowering regimens based on different drug classes. Mean blood pressure differences between the first and second treatment regimens are shown. Negative blood pressure values indicate lower pressures with the first treatment listed. ACEi = angiotensin-converting enzyme inhibitor; CCB = calcium channel blocker; CI = confidence interval; D/ßB = diuretic- and/or beta-blockerbased regimens. Reproduced from the Blood Pressure Lowering Treatment Trialists' Collaboration (2), with permission.