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Figure 3 Change of developed (filled lines) and diastolic (dashed lines) isometric force of left ventricle (LV) (A) and right ventricle (RV) (B) endocardial trabeculae from baseline to peak response to isoproterenol perfusion (1 µg/ml). Left ventricular assist device (LVAD) support resulted in significantly increased developed isometric force generation in both the LV and RV muscle. (C) Change in isometric developed force generation after isoproterenol perfusion. Ruled bars = nonfailing hearts; black bars = medical support; open bars = LVAD support. All data are mean ± SEM. *p < 0.01, {dagger}p < 0.05 vs. medical support.





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