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Figure 1 Time course of systolic blood pressure (A) and pulse rate (B) in sham-operated rats (closed triangles) and in rats with myocardial infarction (MI) before and during infusion of 0.1 µg/kg/min C-type natriuretic peptide (CNP) (closed circles) or vehicle (5% glucose solution) (open squares). Values are mean ± SEM. A p value for systolic blood pressure by two-way analysis of variance: group <0.001; time course <0.001; group/time course interaction <0.001, and a p value for pulse rate by two-way analysis of variance: group <0.05; time course <0.001; group/time course interaction <0.01. **p < 0.01, *p < 0.05 compared with the sham-operated group at same stage by Bonferroni multiple-comparison t test. BPM = beats/min.
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