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Figure 3 Data from a Group 2 dog with a non-critical left anterior descending stenosis at peak dobutamine dose where myocardial blood flow is increased. (A) Perfusion defect early (1 s) after microbubble destruction (arrows) that is similar in topology to the hypoperfused zone by radiolabeled microsphere (B). (C) Perfusion defect later (5 s) after microbubble destruction is partly filled by collateral blood flow. The region still not filled (arrows) corresponds to that with abnormal wall thickening (defined by chords and arrows) (D).
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