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Figure 4 (Left) Adjusted odds ratio (95% confidence interval) for death at two years for non–ST-segment elevation acute coronary syndromes patients with elevated NT-proB-type natriuretic peptide (NT-proBNP) in relation to when NT-proBNP is measured. The odds ratio applies to a doubling of NT-proBNP level at each time point (e.g., an NT-proBNP level at inclusion of 800 ng/l vs. 400 ng/l is associated with a 1.4-fold higher risk of subsequent death, compared with a 1.9-fold higher risk for a similar increase in NT-proBNP level at six months). Adjustment is made for age, gender, diabetes, previous myocardial infarction, creatinine level, ST-segment depression, cardiac troponin T, and C-reactive protein elevation. (Right) Mortality from time of blood sample to end of follow-up at two years in relation to two different cut-offs of NT-proBNP. HC = high cut-off: 1,000 ng/l; URL = upper reference level: 184 ng/l for men and 268 ng/l for women.
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