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Figure 4 Point estimates for change in risk of total mortality (left panels) and number of patients hospitalized for worsening heart failure (right panels) with metoprolol controlled release/extended release (CR/XL) compared with placebo and 95% confidence intervals (Cox adjusted) in relation to net change heart rate (upper panels) and percent net change in heart rate with metoprolol CR/XL (lower panels) in the five quintiles (Q) defined by baseline resting heart rate. For number of deaths and number of patients hospitalized in the two randomization groups in each quintile, see Figures 3 and 5. bpm = beats/min; CHF = chronic heart failure.





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