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Figure 4 Targeted inhibition of phosphoinositide-3 kinase (PI3K) reduces cardiac chamber size. Bar graphs showing (a) body weight (BW), (b) left atrium (LA) weight, (c) left ventricular weight/body weight (LV/BW), (d) heart weight/body weight (H/BW) in wild type (WT) mice, single calsequestrin (CSQ) transgenic, and binary CSQ/catalytically inactive phosphoinositide 3-kinase ${gamma}$ (PI3K ${gamma}$ _inact) transgenic mice. *p < 0.0001 WT vs. CSQ or CSQ/PI3K ${gamma}$ _inact; ${dagger}$ p < 0.01 CSQ/PI3K ${gamma}$ _inact vs. CSQ (analysis of variance with Neuman-Keuls correction).

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