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Figure 2 Plasma low-density lipoprotein cholesterol (LDL-C) levels according to haplotypes (A) and E670G genotypes (B). (A) Referent indicates subjects homozygous for the most common haplotype (haplotype 2+/+). Haplotype 3–/referent– indicates subjects with neither haplotype 3 nor the reference haplotype; haplotype 3+ identifies heterozygous (N = 35) and homozygous (N = 2) subjects with haplotype 3; haplotype 3+/haplotype 2– denotes subjects with haplotype 3 but no haplotype 2. Mean values of LDL-C, standard deviation of the mean, and the number of subjects are indicated in each graph. The results of pairwise t test are shown. (B) The mean values among the three genotypes were compared by analysis of variance and depicted. Pairwise comparisons showed statistically significant differences between AA and GG (p = 0.007) as well as between AG and GG (p = 0.011), but not between AA and AG (p = 0.321).
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