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Figure 3 Effect of high-dose folate on coronary dilator reserve. Dilator reserve was measured in normal (WNL) and abnormal (ABNL) regions. Mean data and standard error bars are depicted. Folate increased dilator reserve by ~83% in abnormal segments (0.72 ± 0.60 ml/min/g vs. 1.31 ± 1.08 ml/min/g, mean ± SD, placebo vs. folate, p < 0.05), whereas dilator reserve in normal segments remained unchanged (2.00 ± 0.61 ml/min/g vs. 2.12 ± 0.69 ml/min/g, placebo vs. folate, p = NS). Open bars = placebo; solid bars = folate.





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