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Figure 8 Expression of tissue factor (TF) (A) and generation of prothrombin fragment (F1+2) (B) by monocytes taken from healthy subjects (n = 4) and stimulated with CD40 ligand (CD40L) (50 ng/ml) or CD40L plus diphenyliodonium (DPI) (15 µmol/l), eicosatetraynoic acid (ETYA) (35 µmol/l), and wortmannin (0.1 µmol/l). *p < 0.0005 for CD40L (50 ng/ml) + DPI (15 µM) versus CD40L (50 ng/ml). **p < 0.0001 for CD40L (50 ng/ml) + wortmannin (0.1 µM) versus CD40L (50 ng/ml).
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