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Figure 6 (A) Effectof isoproterenol (ISO) on ICa in control and aorto-pulmonary artery shunt (APS) states: initial (open circles) and steady-state effects of 1 µM isoproterenol (solid circles). (B) Current densities before (open bars) and at steady state effects of isoproterenol (hatched bars, +ISO) in the control (19 cells from 7 animals) and APS (27 cells from 9 animals) states. *p < 0.05; ***p < 0.0001. (C) Effect of isoproterenol (solid circles, 4-min exposure) on A-type action potential (AP) in the control state, on B- and D-type AP in the APS state.
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