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Figure 6 Cellular sources of MMP and TIMP (A to F). Double labeling for MMP-1 (green) (A) and vimentin (red) (B) showing that fibroblasts are the majority of cells in the MMP occupied area. Serial sections stained for MMP-2 (green) (C) and vimentin (red), CD68 (green) (D). Note: most of the cells in the MMP containing regions are fibroblasts and only a few macrophages are present (arrows). Sequential staining for TIMP (TIMP-1 shown as an example) (green) (E) and vimentin (red) (F) demonstrating fibroblasts in TIMP-positive areas. Nuclei are blue. Abbreviations as in Figure 1.
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