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Figure 5 (A) Results of immunohistochemical staining of the infarcted sites of the myocardial infarction rats treated with saline (MI/C) and MI treated with romurtide (MI/Ro), and of the left ventricle (LV) of the sham-operated rats (Sham) and Sham treated with romurtide (Sham/Ro) on day 7 with use of monoclonal anti-ED-1 and anti-monocyte chemoattractant protein-1 (anti-MCP-1)antibodies (magnification 400x). The ED-1-positive macrophages and MCP-1-positive cells are stained brown. (B) Mallory-Azan staining in the infarcted sites of the MI animals (MI/C and MI/Ro) and in the LV of the sham animals (Sham and Sham/Ro) on days 7 and 14 (magnification 400x). Fibrous tissue appears blue. (C) Collagen content in the infarcted and non-infarcted sites of MI/C and MI/Ro and in the LV of Sham and Sham/Ro (n = 4 per group). Values are mean ± SEM. *p < 0.05 versus Sham;  p < 0.05 versus Sham/Ro;  p < 0.05 versus MI/C.
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