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Figure 4 Effects of romurtide administration on monocyte chemoattractant protein (MCP)-1, transforming growth factor (TGF)-ß1, and collagen type I and collagen type III messenger ribonucleic acid (mRNA) expression in the infarcted and non-infarcted sites. Quantitative analyses showing (A) MCP-1, (B) TGF-ß1, (C) collagen type I, and (D) collagen type III mRNA expression in the infarcted sites and (E) MCP-1, (F) TGF-ß1, (G) collagen type I, and (H) collagen type III mRNA expression in the non-infarcted sites with real-time reverse transcription polymerase chain reaction analyses among sham-operated rats (Sham), Sham treated with romurtide (Sham/Ro), myocardial infarction rats treated with saline (MI/C), and MI treated with romurtide (MI/Ro) (n = 5 per group). Values are mean ± SEM. *p < 0.05 versus Sham; {dagger}p < 0.05 versus Sham/Ro; {ddagger}p < 0.05 versus MI/C. Continued on next page.





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