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Figure 6 Example of time-intensity curve showing the difference between the mean acoustic intensity (AI) of the entire lumen (dark line) and the central lumen (gray line) regions (A), and transverse images of carotid artery after PESDA and Definity microbubbles (MB) injection in the setting of hypertriglyceridemia (B). Note the retention of PESDA MB around the vessel, not seen with Definity. Amplification of the curves in the late period after PESDA MB injection (arrow) demonstrates a resulting positive value of mean endothelial AI. On the other hand, after Definity MB injection the central lumen AI was slightly higher than the entire lumen AI with a resulting negative value of endothelial AI.
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