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Figure 2 A. Representative micrographs of coronary arteries with Azan-Mallory stain at 30 weeks. Arterial wall thickness and perivascular fibrosis were greater in the OLETF rat (middle) than in the LETO rat (left). However, the coronary arterial remodeling was less in the treated-OLETF rat. (right). Scale bar is 50 µm. B. Wall-to-lumen ratio (left) and degree of perivascular fibrosis (right) in LETO, untreated-OLETF, and treated-OLETF rats. Values are expressed as mean ± SD (n = 5 for each group). *p < 0.05 versus LETO rats;  p < 0.05 versus untreated-OLETF rats. Abbreviations as in Figure 1.
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