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Figure 6 Time course of endothelial progenitor cell (EPC) capture. (A) Endothelial progenitor cells originate in the bone marrow and circulate postnatally in peripheral blood at concentrations of 3 to 10 cells/mm3. (B) Anti-CD34 antibody-coated stents, once deployed, have the ability to bind EPCs to their surface. (C) Over time, EPCs bound to the endoluminal surface of the stent proliferate and migrate to fill the intra strut spaces establishing a confluent, functional endothelial cell monolayer on the stented arterial segment.





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