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Figure 3 Laser Doppler blood flow (LDBF) analysis was performed serially in each mouse to determine the blood flow in unilateral ischemic hindlimb. (A) Representative LDBF images of the ischemic (arrow heads) and nonischemic hindlimb in 7ND-transfected and mock-treated mice. (B) Pooled data of temporal changes in ischemic/nonischemic LDBF ratio. The recovery of LDBF ratio was deteriorated by 7ND overexpression in a dose-dependent manner. *p < 0.05 and **p < 0.01 vs. mock-treated mice. Bar = 1 x SD (n = 12).





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