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Figure 2 Renin-angiotensin system inhibition and metalloprotease 9 (MMP9). Concentration of serum MMP9 protein was determined by enzyme-linked immunosorbent assay and its serum activity was fluorometrically analyzed by enzyme immunosorbent assay zymography. Patients were treated for 3 months with either 20 mg enalapril (white bars) or 300 mg of irbesartan (black bars) and blood samples were drawn at baseline and at 3 months. Bar graphs summarize individual  -changes in serum MMP9 and MMP9 activity over a three-month observation period. Data are given as mean ± SEM.
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