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Figure 2 Plasma concentrations of RSD1235 after infusion in patients dosed at 2 mg/kg intravenously (inverted triangles) and those additionally dosed at 3 mg/kg intravenously (circles). The RSD1235 doses were infused over 10 min, as indicated in the text. Initially, a 2-mg/kg infusion was given, and, if required, an additional 3 mg/kg was infused 30 min later in the RSD-2 group. Time is shown relative to the end of the first infusion (T1).
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