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Figure 2 Representative traces of cell shortening in isolated cardiomyocytes from four groups, evoked by electrical stimulation under perfusion conditions of 37°C, [Ca2+]0 was 1.8 mmol/l, and the pacing rate was 1.0 Hz. The electrical stimulation was applied at the arrow. (A) Cont. (B) Cont+UL. (C) DOX. (D) DOX+UL. Note that the time courses of cell shortening and relaxation are extremely prolonged in DOX and have recovered in DOX+UL. Abbreviations as in Figure 1.
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