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Figure 7 Proliferation of OPN–/–-derived fibroblasts is blunted versus WT cells. Osteopontin-null cells grown in the absence of exogenous OPN had a significantly reduced proliferative response to serum stimulation versus WT-derived cells, whereas OPN–/– cells grown in the presence of exogenous OPN had proliferative capacities not significantly different from WT values. *p < 0.05 vs. WT. Abbreviations as in Figure 1.





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