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Figure 1 Validation example from a swine experiment. (A) Greyscale M-mode recording. The electrocardiogram (bottom) and synchronicity (top) signals are shown. Micromanometer echoes are visualized in the mid-cavity and left ventricular outflow tract (LVOT), and were confirmed by two-dimensional sequences acquired simultaneously. (B) Raw color M-mode Doppler image. (C) Parametrical intraventricular pressure gradient (IVPG) ({delta}p/{delta}s) image overlay on the greyscale figure of A. The sign and magnitude of the gradient is given by the color bar, representing the ejection intraventricular pressure difference ({Delta}P) between each pixel and another one located 1 cm closer to the transducer. The equivalent location of the three micromanometers in this IVPG field has been traced (dashed lines). (D, E, and F) The {Delta}P curves between the sensor locations represented in C, obtained by micromanometers (thin lines) and by Doppler-echocardiography (thick lines). Ejection onset and end are shown (dashed lines in B and ticks in C to F). Curve parameters analyzed in the present study are displayed in D.





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