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Figure 5 Representative current traces of the E-4031-insensitive current, as IKs, in rabbits of the control (a) and beta groups (b). The IKs elicited by the voltage-clamp protocol in the inset was normalized to the cell capacitance. Measured maximum outward tail currents were averaged and plotted against the test potential (c). The IKs density obtained in the beta group rabbits was significantly smaller than that in the control group rabbits. (Data were obtained from isolated left ventricular myocytes from the M-cell region.) C = control.





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