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Figure 1 (A) Representative tracings of left ventricular M-mode echocardiograms of the sham group at the age of 11 weeks (upper left) and 17 weeks (upper right), the myoblast transplantation (MB) group (lower left), and the transplantation of CT-1–expressing myoblasts (MB + CT) group (lower right) at the age of 17 weeks. Left ventricular dilation and contractile dysfunction were attenuated in both MB and MB + CT groups at the heart failure stage (six weeks after transplantation). (B) Serial measurements of echocardiography in the sham, MB, and MB + CT groups. A p value by two-way analysis of variance: group <0.001; time course <0.001; group/time course interaction <0.001 for each parameter. *p < 0.05 and **p < 0.01 vs. sham group;  p < 0.05, and p < 0.01 vs. MB group at same stage by Bonferroni's multiple-comparison t test. Values are means ± SEM. EDD = end-diastolic diameter; FS = fractional shortening; PWT = posterior wall thickness; W = the age (weeks).
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