Please click here to obtain permission to reproduce this image.
Click on image to view larger version.
Figure 5 The ethylenediaminetetraacetic acid (EDTA), cytochalasin D, and GM6001 inhibit the release of sCD40L from the surface of activated platelets. Released sCD40L in platelet rich plasma, in the presence of 50 µM isoTRAP and either no inhibitor, EDTA 5 mM, cytochalasin D 60 µM, or GM6001 30 µM, was measured as in Figure 2. (A) Inhibitors added before isoTRAP. (B) Inhibitors added 3 min after isoTRAP. Data are mean ± SEM, n = 3. Asterisks indicate significance as compared with no inhibitor.
|
