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Figure 7 (A) Immunohistochemical staining for hHGF in transplanted NIH3T3 cells (panel a) and NIH3T3 + hHGF + TK cells (panel b) in the skeletal muscle. Scale bars = 50 µm. (B) The NIH3T3 + hHGF + TK (107) cells were transplanted, and two weeks later, various concentrations of ganciclovir were administered for another four weeks. (C) Hematoxylin-eosin staining. (Panels a to c) The natural history of the transplanted NIH3T3 + hHGF + TK (107) cells is shown. (Panels d to f) Beginning two weeks after transplantation, ganciclovir (50 mg/kg/day) was administered orally for two to four weeks. The cells had completely disappeared after four weeks of ganciclovir treatment. Arrows indicate the microvessels. Scale bars = 100 µm. Abbreviations as in Figure 1.
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