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Figure 6 (A) Representative laser Doppler perfusion images. (B) Quantitative analysis of the rate of blood perfusion of the ischemic/nonischemic limb. Panel a = Control mouse on postoperative day 1; panels b to f = four weeks after treatment (panel b = saline injection; panel c = NIH3T3 transplantation [107 cells]; panel d = NIH3T3 + hHGF + TK transplantation [104 cells]; panel e = NIH3T3 + hHGF + TK transplantation [107 cells]; panel f = beginning two weeks after transplantation of NIH3T3 + hHGF + TK (107 cells), ganciclovir (50 mg/kg/day) was administered orally for four weeks. Oral ganciclovir administration adjusted the blood perfusion rate of the ischemic limb to the same level as that of the nonischemic limb (eight mice/group). *p < 0.01,  p < 0.001 vs. saline,  p < 0.05, ¶p < 0.01 versus NIH3T3. Abbreviations as in Figure 1.
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