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Figure 3 (A) Quantitative gelatinase assay. (Left panels) Comparison between early heart failure (HF) and respective controls. (Right panels) Comparison between severe HF and respective controls. (Upper panels) Left atrium (LA). (Lower panels) Right atrium (RA). *p < 0.01 versus respective controls; p = 0.05 versus control. (B) Effect of protease inhibition on gelatinase activity. Data are means of triplicate assays. There is 100% inhibition of gelatinase activity with GM6001, an matrix metalloproteinases inhibitor.
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