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Figure 1 (A) The time constant of left ventricular pressure decay (Tau), and (B) left ventricular (LV) pressure–volume (P-V) loops and left ventricular end-diastolic volume measured in vivo with conductance catheter in sham-operated rats (Sham) and in rats with extensive myocardial infarction (P MI): Effects of aldosterone receptor inhibition (E), ACE inhibition (T), or combined aldosterone and ACE inhibition (E+T). Mean ± SEM (n = 6 to 12). *p < 0.05 versus Sham;  p < 0.05,  p < 0.001, p = 0.0001 versus P MI; #p < 0.05 versus E MI; **p = 0.059 versus T MI.
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