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Figure 3 (A) Receiver operator characteristic curves obtained from the post-flecainide QTc in each lead. The value of the QTc interval in V2 has the greatest accuracy in discriminating negative from positive electrocardiograms (ECG) (see text for details). (B) Distribution of QTc intervals in V2 after flecainide administration. A QTc interval in V2 of >464 ms in females and >442 ms in males identified a positive ECG with 100% sensitivity and specificity. Closed circles = females with a positive test; open circles = females with a negative test; closed triangles = males with a positive test; open triangles = males with a negative test.





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